Q: A gene string can be represented by an 8-character long string, with choices from 'A', 'C', 'G', and 'T'.
Suppose we need to investigate a mutation from a gene string start to a gene string end where one mutation is defined as one single character changed in the gene string.
- For example, "AACCGGTT" --> "AACCGGTA" is one mutation.
There is also a gene bank bank that records all the valid gene mutations. A gene must be in bank to make it a valid gene string.
Given the two gene strings start and end and the gene bank bank, return the minimum number of mutations needed to mutate from start to end. If there is no such a mutation, return -1.
Note that the starting point is assumed to be valid, so it might not be included in the bank.
A: BFS (Breadth-First Search)139Please respect copyright.PENANA7sWHhi0kHf
// better than use DFS as it just need to find out the shortest path.
class Solution {139Please respect copyright.PENANA8BOr3fWP99
public int minMutation(String start, String end, String[] bank) {139Please respect copyright.PENANANc2fy5WPRi
// Initialize a queue queue and a set seen. The queue will be used for BFS and the set will be used to prevent visiting a node more than once. Initially, the queue and set should hold start.139Please respect copyright.PENANA4G30Kwv1hG
Queue<String> queue = new LinkedList<>();139Please respect copyright.PENANAlFahuG9UUa
Set<String> seen = new HashSet<>();139Please respect copyright.PENANAS3STkgqCOK
queue.add(start);139Please respect copyright.PENANAhG6lKlR5cM
seen.add(start);139Please respect copyright.PENANAoOnG7GgNWK
139Please respect copyright.PENANA0NORj9tQ4a
int steps = 0;139Please respect copyright.PENANAbgV18abgzX
139Please respect copyright.PENANAjGUN4IzNJB
while (!queue.isEmpty()) {139Please respect copyright.PENANAWIQKzsrxeg
int nodesInQueue = queue.size();139Please respect copyright.PENANAmcAHkjdKg0
for (int j = 0; j < nodesInQueue; j++) {139Please respect copyright.PENANAKBUpdJnGty
String node = queue.remove();139Please respect copyright.PENANASUm3tGYJ1O
// Perform a BFS. At each node, if node == end, return the number of steps so far. Otherwise, iterate over all the neighbors. For each neighbor, if neighbor is not in seen and neighbor is in bank, add it to queue and seen.
if (node.equals(end)) {139Please respect copyright.PENANA1hCra56RR5
return steps;139Please respect copyright.PENANAiH6aPqOLrt
}
for (char c: new char[] {'A', 'C', 'G', 'T'}) {139Please respect copyright.PENANAXXKMRw1sDT
for (int i = 0; i < node.length(); i++) {139Please respect copyright.PENANArOk2rDJApf
String neighbor = node.substring(0, i) + c + node.substring(i + 1);139Please respect copyright.PENANAhs5Zo68Yci
if (!seen.contains(neighbor) && Arrays.asList(bank).contains(neighbor)) {139Please respect copyright.PENANAGkaAOILmSC
queue.add(neighbor);139Please respect copyright.PENANAJ5pLejX4Eq
seen.add(neighbor);139Please respect copyright.PENANAtMN4big9wr
}139Please respect copyright.PENANAEZbVERub2m
}139Please respect copyright.PENANAqNYJSQxBVU
}139Please respect copyright.PENANABBPYZmzet7
}139Please respect copyright.PENANAP2Htq3uWiY
139Please respect copyright.PENANAUStnjf76KG
steps++;139Please respect copyright.PENANAgm9SGrCAOa
}139Please respect copyright.PENANA9x1AiMspbw
// If we finish the BFS and did not find end, return -1.139Please respect copyright.PENANAW60aweXrMi
return -1;139Please respect copyright.PENANAvCXRITxz6e
}139Please respect copyright.PENANA36cuf8GcOO
}