What is Opana ER?1767Please respect copyright.ＰＥＮＡＮＡyzlGO8oSVi
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Opana ER is the extended-release formulation of oxymorphone drugs. Opana ER is a long-acting opiate. Opioids work in the brain to change the way your body feels and responds to pain sensations. Extended-release formulations of medicines are not for "as needed" use. They are long-acting agents used to treat patients in the long run.1767Please respect copyright.ＰＥＮＡＮＡicGVxfwsL8
Opana ER pills boost the level of certain neurotransmitters (GABA) in the brain. Gamma Amino Butyric Neurotransmitter is responsible for sending relief signals in the brain and nerves. Opana pills increase the GABA receptors, which in turn impact the messages of calmness and pain relief to the body and mind.1767Please respect copyright.ＰＥＮＡＮＡZ10EOoU8wu
What is the Use of Opana ER?
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Opana ER is a long-acting opioid agonist for the management of severe pain. Extended-release tablets are helpful in the treatment of severe chronic pain that requires around the clock pain relief treatment and not for the pain that is short-term or can be treated with non-opioid or immediate-release opioids analgesics.1767Please respect copyright.ＰＥＮＡＮＡrdN9fHt1bI
Limitations of Use1767Please respect copyright.ＰＥＮＡＮＡlp3OmFiMLQ
Opana ER is only for use in patients for whom other treatment options such as non-opioids or immediate-release opioids are not tolerated, ineffective, or inadequate to provide sufficient pain relief.1767Please respect copyright.ＰＥＮＡＮＡhvbg2dOYhd
The medication possesses a high risk of addiction, abuse, and misuse, even at prescribed dosages. Overdose of Opana ER pills can lead to severe medical issues and even death.1767Please respect copyright.ＰＥＮＡＮＡvepcHD58Pc
Opana ER is not used as a pen ("as needed") analgesic.1767Please respect copyright.ＰＥＮＡＮＡ8DH70GWUWV
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How to Use Opana ER?1767Please respect copyright.ＰＥＮＡＮＡFoV4w492M3
- Take Opana ER only on prescription by a health care expert who knows opioid use and management.
- Doctors should administer the lowest beneficial doses for the shortest duration to avoid the risk of dependence, addiction, and abuse.
- Dosages of Opana ER are individualized according to the intensity of pain, medical status, and general condition of the patient.
- Take the pills on an empty stomach, at least 2 hours after eating or 1 hour before eating.
- Swallow one tablet at a time with the required amount of water.
- For opioids, non-tolerant patients, start the treatment with 5mg pills given orally every 12 hours.
- For patients converting from other opioids to Opana ER, doctors should use conversion factors to estimate the starting dose.
- Increase the doses every 3 to 7 days, with increments of 5 to 10 milligrams every 12 hours, as required and tolerated by a patient.
- When a person needs to discontinue the treatment of Opana ER tablets, he/she should consult the doctor. A doctor reduces the doses gradually to prevent symptoms of withdrawal. Abruptly stopping the medication causes withdrawal symptoms.
- For the patients with mild hepatic impairment and renal impairment, initiate the dose with 5mg given every 12 hours. Titrate the doses slowly to achieve maximum analgesia. Closely monitor patients for the signs of respiratory and central nervous system depression.
- For geriatric or debilitating patients, start the dose with 5mg given orally every 12 hours. cautiously increase the doses while monitoring for the signs of respiratory and central nervous system depression and other adverse effects.
What are the Contraindications of Opana ER Pills?1767Please respect copyright.ＰＥＮＡＮＡAqWySDPj0P
- Opana ER pills contraindicated in patients with:
- Acute or severe asthma
- Respiratory depression
- Hypersensitivity to oxymorphone
- Known sensitivity to opioids
- Hypersensitivity to inactive ingredients of the medicine
- Acute or severe hepatic impairment
- Gastrointestinal obstruction
- Paralytic ileus
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List of Adverse Reactions of Opana ER1767Please respect copyright.ＰＥＮＡＮＡGpkyzjDihz
The adverse reactions associated with Opana ER use include:
- Nausea
- Vomiting
- Constipation
- Giddiness
- Somnolence
- Excessive sweating
- Headache
- Dry mouth
- Sedation
- Insomnia
- Fatigue
- Decreased appetite
- Abdominal pain
What major drugs interact with Opana ER pills?1767Please respect copyright.ＰＥＮＡＮＡfL7sGZc51o
Many drugs interact with Opana ER tablets. The significant drug interactions of the pills include:
- Serotonergic drugs
- Mixed agonist opioids
- Partial opioid analgesics
- Monoamine Oxidase Inhibitors (MAOIs)
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