Thrown out after getting pregnant, sixteen-year-old Hope faces an uncertain future on the streets. But when she meets a mysterious man who claims to come from a planet called Pandora, her life is changed forever. She isn't quite sure whether or not to believe him, though, until the day the ship arrives to carry her and other young women into space and a new life. But when they reach Pandora, things truly change for Hope and her companions.

For Pandora is a world with almost no women, thanks to a rare disease that has been slowly killing them off for generations, and rendering the survivors infertile. The women from Earth are like a gift from the gods to the men, but when the Earth women also succumb to the disease - either killing them or making them infertile - new problems arise, not just for them, but for Hope - who is the only woman not to lose her baby. Now she must face a choice - see her child surrendered to the whims of Pandora's rulers, or go on the run and defy destiny once more.