油並無法容易溶於水裡,因此當脂肪從我們身體的血液循環系統時,便需要依靠蛋白質的輔助,合體成為脂蛋白(Lipoprotein),才能方便於血液中流動行走。768Please respect copyright.PENANAZ1aPQYsomy
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(圖2)根據密度及體積,脂蛋白可分成為不同種類。768Please respect copyright.PENANAsgmmSRx1eF
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Low Density Lipoprotein(LDL)主要負責從肝臟把油脂傳送到各器官,而血液LDL含量長期高企的話,患上心臟病或中風的機會亦會高企,因此經常被冠稱為壞膽固醇。768Please respect copyright.PENANA0g41NTLvDa
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而當細胞尤其是肝臟細胞內的膽固醇過多的話,便會以High Density Lipoprotein(HDL)的形式排出細胞外。768Please respect copyright.PENANArAc15Zl8Gp
細胞內含有過多膽固醇的話便會觸發細胞進行死亡的機制,基於HDL能把它們帶出細胞外,避免壞事發生,因此亦被稱之為好膽固醇。768Please respect copyright.PENANA6LY0zULCD3
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(圖3)細胞可從外間直接攝取膽固醇,又或者是從其他原料自行製作膽固醇。768Please respect copyright.PENANAMKR6xA4RRj
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降膽固醇藥Statin能夠抑制其中一隻參與製作膽固醇過程的酶素,導致膽固醇的製作無法順利完成。768Please respect copyright.PENANAeTblMsn8pq
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而細胞在藥物的誤導下,以為是自己因為吸收不足夠的LDL,所以無法製作膽固醇,因此便會增大吸收外間LDL的能力,得出的結果就是把血液裡的壞膽固醇含量大幅度下降。768Please respect copyright.PENANAYGCaphoeq2
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能降低血液LDL含量固然是一件好事,畢竟血液LDL含量與心臟病中風等疾病有著密切的關聯。768Please respect copyright.PENANAIRddyHo2fN
但亦有一些統計數據指出服用Statin會增加患癌風險,其機制現時尚未能搞得清楚。768Please respect copyright.PENANASUivYMqCDN
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Statin藥物所抑制的製作膽固醇的機制,箇中亦包含其他有用的有機物及代謝物製作。768Please respect copyright.PENANAMfxmfknGeJ
干涉到那些有機物的製作會否促成癌症生長,還需要大量的研究作出探討。768Please respect copyright.PENANA2IX8Z1yhXU
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如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。768Please respect copyright.PENANANMvleSRjfM
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc768Please respect copyright.PENANAY0vXOkRhzX
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。768Please respect copyright.PENANA4Nj51x9dKZ
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Link:768Please respect copyright.PENANAzCBGOYvgmJ
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio768Please respect copyright.PENANAD9urA7lIxQ
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除非Facebook及IG重開侵侵的account,否則我的IG將不會再作更新,只會寄居本土LIHKG及Penana。768Please respect copyright.PENANABSaU7rJP4P
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Ref1:https://pubmed.ncbi.nlm.nih.gov/8561503/768Please respect copyright.PENANApIRivvFN60
Ref2:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225778/768Please respect copyright.PENANARU1yniyJbd