當血壓長期處於過高狀態的時候,便有機會出現心臟肥大(Cardiac hypertrophy)的情況。373Please respect copyright.PENANAQA0lFsOG37
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(圖2)心臟的肌肉會利用收縮及膨脹的舉動把血液送到全身,如果血壓高企的話,心臟肌肉細胞便會自行膨脹增大,好使心臟有更強力量抵禦血液帶來的壓力,且能繼續維持正常功能把血液送往全身。373Please respect copyright.PENANAFmjGCIEggY
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這現象稱之為心臟肥大(Cardiac hypertrophy)。373Please respect copyright.PENANAUjjtpgQkiu
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(圖3)當血壓持續高企及攀升到某一個位,心臟的肌肉再也沒法透過膨脹增大來維持運作,這時候心臟便會進入「放棄人生」的狀態,再也不會激烈地膨脹收縮,形成心臟衰竭(Heart failure)局面,血液因而再也沒能輸送到身體各部位。373Please respect copyright.PENANAyWSxYCCnag
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換句話說,長期因高血壓所造成的心臟肥大(Cardiac hypertrophy),會是形成心臟衰竭(Heart failure)的其中一道誘因。373Please respect copyright.PENANAmNWGYRK24p
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(圖4)有見及此,有不少科學家會以人工方式在動物模型上製造心臟肥大(Cardiac hypertrophy)的局面,藉此了解箇中對細胞所做成的影響,從而找出防止下一步心臟衰竭(Heart failure)的潛在發生。373Please respect copyright.PENANA9147nrUfI9
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其中的一種手段,就是利用縫線的手法局部減低心臟血管血液流動的動向。373Please respect copyright.PENANAb7eEEeYHB3
從圖中可見,縫線後左心房所承受的血壓將會大幅度增強。373Please respect copyright.PENANAM9tBQHKTzQ
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(圖5)圖中可以清晰見得到,縫線後左心房的確出現肥大的狀況。373Please respect copyright.PENANAuVgB3Zp6fx
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而這些動物的付出,確實是為人類的健康作出了非常大的貢獻,下集將會再作進一步的講解。373Please respect copyright.PENANAUfitlpmEpu
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Ref1:https://pubmed.ncbi.nlm.nih.gov/12738623/
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