隨著針對癌細胞新陳代謝的研究逐漸倍增,配合飲食來醫治癌症這方面亦開始得到關注。439Please respect copyright.PENANAbldicyuE9S
439Please respect copyright.PENANAdUzLbiihDM
439Please respect copyright.PENANAuL204cLsaF
現今有不少利用實驗室細胞及動物的研究指出,低卡路里餐單能加強化療藥物醫治癌症的效果。科學家們對此曾提出不少理論試圖解釋這現象,但現今並沒有一道能獲取大部份人共識的理論。439Please respect copyright.PENANA1MUrMBEDPF
439Please respect copyright.PENANA0zwC9q7fYL
(圖2)有一項人體臨床研究找來129名乳癌病人(Ref1),65人在療程中進食低卡路里餐單,而另外64人則沿用正常餐單。439Please respect copyright.PENANAbsb47qVloO
439Please respect copyright.PENANAVcNF0dBEPN
439Please respect copyright.PENANAzffsbt1vfi
奈何因為味道及食慾等問題,最終只有22人能夠忍耐低卡路里餐單4星期,13人能夠忍耐8星期整個研究進程。439Please respect copyright.PENANA0kDeTjzbyO
439Please respect copyright.PENANAxjsDAtZQQX
正常餐單那方,亦有5名病人想在療程中途嘗試一下低卡路里餐單。439Please respect copyright.PENANAwH1IoHuaAe
439Please respect copyright.PENANAaVtMOMEIgl
(圖3)圖中為低卡路里餐單的時間表。第一日攝取的總卡路里為1200,而之後的三日則為200卡路里,以碳水化合物為主。439Please respect copyright.PENANAxzyOwX4Nur
439Please respect copyright.PENANAnegfn0rAS3
439Please respect copyright.PENANAylWA81pWwH
第四日將會進行化療,而整個週期將重覆8次。439Please respect copyright.PENANAnA7Vv02qdb
439Please respect copyright.PENANACIMppI9Atr
(圖4)文中並沒有列出正常餐單的成份,但從文中結果的血液各指標中可以看得到,低卡路里餐單的病人,血液酮體含量比正常餐單的病人為高,而胰島素含量則為低。439Please respect copyright.PENANACDx7hece8K
439Please respect copyright.PENANA8UMOUXjz0U
439Please respect copyright.PENANAJRS7AVqliY
這至少證明了低卡路里餐單的病人是一直處於「飢餓」的狀態。439Please respect copyright.PENANA3pA0cMQheg
439Please respect copyright.PENANAdM79ILTJhn
439Please respect copyright.PENANAu2555rOoob
(圖5)遵從低卡路里餐單的病人,化療3小時之後,某一組別的免疫細胞所受到的DNA傷害比正常餐單的人為低,為正面的良好效果。439Please respect copyright.PENANABNUsqSLFvr
439Please respect copyright.PENANAuSXZifUGVj
439Please respect copyright.PENANALzgaxuJyVU
但低卡路里餐單能否使化療效果事半功倍,還需要更多的病人數量才能得出結論。439Please respect copyright.PENANA5MUsUX191D
439Please respect copyright.PENANAGKp4rR7z3r
另一方面,開發出能夠讓病人廣泛接受的低卡路里餐單,亦是一道需要關注的問題。439Please respect copyright.PENANAbiGPfd639Y
439Please respect copyright.PENANAka3H33L9Ww
有興趣接收科學資訊的話,歡迎follow IG: potatopigtongue。439Please respect copyright.PENANAraij4bnBTe
439Please respect copyright.PENANAjAItsluDtW
https://www.instagram.com/potatopigtongue/439Please respect copyright.PENANADTQwKkSUFa
439Please respect copyright.PENANAWANVucfwox
Ref1:https://www.nature.com/articles/s41467-020-16138-3#Sec20439Please respect copyright.PENANA3RMcshEn5g