注射武肺疫苗的主要目的,就是誘導身體產生對抗武肺病毒的抗體。428Please respect copyright.PENANALNfr9slKlk
428Please respect copyright.PENANAXQLjg7mUT7
428Please respect copyright.PENANAkvW4jDBoTn
但身體製造抗體需時,而且免疫系統薄弱的人士亦有可能沒法製造足夠數量的抗體。在這層面上,直接注射人造抗體的話,便能免去這兩道隱憂。428Please respect copyright.PENANA1tK0UtQW0r
428Please respect copyright.PENANAYoyXKnca8T
(圖2)從圖中所見,檢測者身體含有武肺抗體的話,身體的病毒數量相對上亦會較少,反之亦然。428Please respect copyright.PENANAY7IE7Y7JPC
428Please respect copyright.PENANAPBIRGrLVAj
428Please respect copyright.PENANAcnx07Yjtdp
可見病毒數量與體內抗體含量有著反比的關係。428Please respect copyright.PENANADbYCtVNbil
428Please respect copyright.PENANAvvW4UlaGRS
(圖3)現今有一推斷,體內武肺病毒數量越多的話,出現重症的機會亦會相繼增加。428Please respect copyright.PENANAjT6LO2DnV1
428Please respect copyright.PENANAUf5o9DcALj
428Please respect copyright.PENANA30CeOpE4RZ
針對這一點,REGN公司進行臨床測試,為武肺患者注射兩款武肺人造抗體428Please respect copyright.PENANAwYywtS1hsR
casirivimab (REGN10933) 和imdevimab (REGN10987),428Please respect copyright.PENANAQzY0zuZxy5
觀察能否透過注射人造抗體來減低體內病毒的數量(Ref1)。428Please respect copyright.PENANAPX8P2Wog2F
428Please respect copyright.PENANAwniSn42oJS
(圖4)分別往測試者注射安慰劑(灰線)、2g人造抗體(藍線)和8g人造抗體(綠線)後,可以見得到接受人造抗體注射的人士,其病毒在體內的下降速度比注射安慰劑的來得更快。428Please respect copyright.PENANAub1dq3OMGX
428Please respect copyright.PENANAU7Y9UxAE3w
428Please respect copyright.PENANA011sDbacBY
(圖5)但若然在注射前已被驗出擁有武肺抗體的話,額外的人造抗體注射並不會導致病毒有顯著的加快下跌(右圖);這有可能是體內的抗體本身已足夠應付現況。428Please respect copyright.PENANArxNvVNDlhU
428Please respect copyright.PENANA0O4fKbOh1t
428Please respect copyright.PENANAme3SzmCVvf
428Please respect copyright.PENANAFzIEHiMXyM
(圖6)值得留意的是,本身病毒數量越多的話,人造抗體所促使的病毒量下跌效果便會越見明顯。428Please respect copyright.PENANA4TXW2j3NCL
428Please respect copyright.PENANAVWJRi12SxR
428Please respect copyright.PENANAxfqR3XxUeH
亦即是代表當體外病毒數量超過某一定數量的時候,體內自身的抗體便會未能足以應付現況,而此時候所注射的人造抗體便會派上用場。428Please respect copyright.PENANAoCAH7p28hA
428Please respect copyright.PENANAJFiZRqbFro
(圖7)人造抗體注射後的第28日,其濃度亦相對非常穩定,能給予注射人士一道保護時間。428Please respect copyright.PENANA5wX1bdXQv3
428Please respect copyright.PENANA18nhE2k2MY
428Please respect copyright.PENANADSOXG49qSJ
428Please respect copyright.PENANAY9W8pBbdHI
人造抗體雖能加快病毒下降的速度,但能否預防重症這一方面並未有充份證據支持。428Please respect copyright.PENANAGGQulAnGOG
428Please respect copyright.PENANACCkPjgBVip
而當患者已出現嚴重症狀後,注射人造抗體能否緩和或解決症狀亦是相當成疑。428Please respect copyright.PENANAf4Tf1PmnR6
428Please respect copyright.PENANA7BLzJpdagh
但無論如何,若然想達到在短時間內減低體內病毒的數量,人造抗體相信是其中一道的選擇。428Please respect copyright.PENANAIqNTz0edB4
428Please respect copyright.PENANAgy3HAGsq59
428Please respect copyright.PENANAkcUFHuPv8O
如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。428Please respect copyright.PENANAPsrFEpoeGB
428Please respect copyright.PENANADwJzf0oLIO
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc428Please respect copyright.PENANAxBe0dEFHE3
428Please respect copyright.PENANAlyC3qNZyIM
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。428Please respect copyright.PENANApJqIiz5S67
428Please respect copyright.PENANAUlgcV6W3SX
Link:428Please respect copyright.PENANA3dpCyOjhaC
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio428Please respect copyright.PENANAAZwQoH1DOF
428Please respect copyright.PENANAwIb1xgPedO
有興趣接收科學資訊的話,歡迎follow IG: potatopigtongue。428Please respect copyright.PENANAbLCO6D9ihJ
428Please respect copyright.PENANAlKOxq6u9zc
https://www.instagram.com/potatopigtongue/428Please respect copyright.PENANAlCbbnkDgkJ
428Please respect copyright.PENANAAu8xoCkH0t
428Please respect copyright.PENANAgWqSiw6iOm
Ref1:https://www.nejm.org/doi/full/10.1056/NEJMoa2035002428Please respect copyright.PENANAe3P3zb8IyZ