黑色的秀髮,最主要是由真黑素(Eumelanin)天然染成。515Please respect copyright.PENANAPbCbPgqpzY
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(圖2)皮膚下的黑素細胞(Melanocyte)會製造出黑色粒子Melanosomes,而這些黑色粒子Melanosomes會走到表皮(Epidermis)或者髮囊(Hair follicile),賦予皮膚及頭髮黑色外表。515Please respect copyright.PENANAuU1HiLlZkY
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(圖3)圖中為Melanosomes裡頭的生物化學反應,起始材料為氨基酸,經過一輪酶素的化學反應後,最終成品將為黑色真黑素及啡色真黑素。515Please respect copyright.PENANAopLHi272MG
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而根據兩者比例的不同,最終的顏色效果亦會有所不同,所以Melanosomes並不一定是純黑色,亦因而解釋了為何並不是所有人的頭髮也是漆黑黑一片。515Please respect copyright.PENANA0mBpXjjDfb
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值得留意的是,這一系列發生在Melanosomes的反應均是在中性pH7的環境下進行,有別於現時常用的鹼性pH化學染髮方式。515Please respect copyright.PENANAlen6IiDcSc
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有科學家看準這一點,因而嘗試照辦煮碗在體外套用我們自身Melanosomes蛋白酶的機制方式進行染髮(Ref1)。515Please respect copyright.PENANAqn4KTDyA9v
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(圖4)從圖中可見,鹼性pH化學染髮以及中性pH7模仿人類Melanosomes裡頭生物化學反應方式染髮(2小時,攝氏35度),兩者最終的外表差別不大。515Please respect copyright.PENANAcgC1aab737
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而且經過5次清水沖洗及10分鐘的洗髮水猛烈沖洗後,兩者亦沒有出現脫色的現象。515Please respect copyright.PENANAHDKAVO8SrL
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只不過,利用鹼性pH化學染髮的話,色素會徹底進入髮質內部。515Please respect copyright.PENANAW9PFcKZG72
反觀中性pH7生物化學反應方式染髮,色素主要聚集在髮質外部,因此對頭髮的傷害相對較低。515Please respect copyright.PENANASNiPjgqBUq
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(圖5)在圖中亦可以清楚看得到,鹼性pH化學染髮對頭髮外部會做成傷害(箭嘴所指位置),515Please respect copyright.PENANAAitYdu3DmP
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而中性pH7模仿人類Melanosomes裡頭生物化學反應方式染髮則沒有這個問題。515Please respect copyright.PENANAtSE9BsTc0d
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此方法能否在日後淘汰鹼性pH化學染髮或其他的染髮手段,我們將可拭目以待。515Please respect copyright.PENANA4aRK0UdocA
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Ref1:https://pubs.acs.org/doi/pdf/10.1021/acs.chemmater.0c02790
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