武漢肺炎病毒現時的主流品種為D614G,一道較為簡易的說明方法就是原來的D614品種變異成為G614品種。543Please respect copyright.PENANAfx2CuzFIfJ
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而根據GISAID公開資料庫記錄,G614品種最先在1月24日的四川病毒樣本出現。543Please respect copyright.PENANAnNsPy2DnkO
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(圖2)何解G614品種能夠成為主流,一直是科學家想解答的問題。543Please respect copyright.PENANApizpydHywe
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之前所獲得的實驗數據,大多是從病毒一小段的部份、或者是合成病毒獲取結果,沒能百分百反映現實。543Please respect copyright.PENANAYmKdyjeV8M
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直至最近,才有科學家利用真實存在的武肺病毒進行實驗。543Please respect copyright.PENANAsZWNV8r2CI
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(圖3)在研究中(Ref1),科學家將D614品種及G614品種以1 : 1的比例從倉鼠的鼻孔注入其體內。543Please respect copyright.PENANAQa8oYeAmRN
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如果最終G614品種/D614品種的比例大於1的話,亦即是代表G614品種在繁殖方面比D614品種更為優勝。543Please respect copyright.PENANAUuumCAAhFU
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(圖4)倉鼠受病毒感染7日後,鼻孔、氣管及肺部個別區域的G614品種/D614品種均大於1,顯示G614品種在上述區域有著較佳的繁殖優勢。543Please respect copyright.PENANAEmXFcREeF6
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同時在實驗室的人體肺部細胞中,就算用上D614品種及G614品種以9 : 1的比例方式感染,G614品種/D614品種在其後感染日子均呈大於1的狀態,更進一步顯示G614品種的繁殖優勢。543Please respect copyright.PENANAEOS5ksXDBx
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(圖5)科學家同時亦發現,G614品種的病毒在各種溫度上均比D614品種相對為穩定。543Please respect copyright.PENANAawVCYt4fKb
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不過好消息是,對抗D614品種的抗體,其對抗G614品種品種效率並無任何損傷。543Please respect copyright.PENANAHoykLigoEW
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這亦即間接顯示出以D614品種作原材料的疫苗,其產生的抗體亦能有效對抗G614品種病毒,而事實上現今亦有疫苗是利用G614品種作原材料,奈何是鄰國出品。543Please respect copyright.PENANAgl9l92yCbO
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(圖6)至於近來在挪威發現的新變種M439K品種,基於是新發現的關係,現時醫學界及學術界均無任何學術文章作詳細研究其特性。543Please respect copyright.PENANA1fVepQr81G
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莫論病毒變種與否,只需一個乞嗤,病毒就已經不需近距離接觸,便能透過體液傳播至他人。543Please respect copyright.PENANAuWU6sXlWhw
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將「新變種」及「不需近距離接觸」串連在一起的報導手法,有著混淆視聽的成份,並不可取。543Please respect copyright.PENANAzY98uyMeDq
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Ref1:https://www.nature.com/articles/s41586-020-2895-3543Please respect copyright.PENANAxS2eXaDIKE