我們身體細胞的DNA,會經過不同蛋白質的幫助下接疊以及壓縮,成為名為染色體(Chromosome)的結構。360Please respect copyright.PENANATlnTtlGAPt
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而這些染色體、亦即是DNA,將會收藏在細胞裡的細胞核。360Please respect copyright.PENANANpsRfe1aNA
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(圖2)細胞進行自我複製時,將會複製自己的DNA,並會暫時性將細胞核的外膜消除。360Please respect copyright.PENANAmb1ElI3qPD
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被複製的DNA會排在中間,然後經由線狀結構(綠色)往左右兩方邁進。360Please respect copyright.PENANAyEhFcCINiA
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(圖3)往左右兩方邁進的染色體,有時候會出現跑得較為慢的染色體(圖中藍色箭嘴)。360Please respect copyright.PENANANfR43rOpPJ
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落後於人的染色體,最終有機會無法加入正常大隊,並自立一閣形成名為micronucleus的結構。360Please respect copyright.PENANAa21tCTPZ7j
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(圖4)這些名為micronucleus的結構,基於其外膜的發展並不完善,因此非常容易會出現損壞的情況。360Please respect copyright.PENANAmzgIGxP1tq
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當外膜受到損毀,裡頭的DNA有極大機會遭受襲擊,因此出現變異的情況。360Please respect copyright.PENANAqPwAuDF8tx
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而這些變異的DNA,往往就是讓正常細胞發展成為癌細胞的契機。360Please respect copyright.PENANArBxSr4BdA9
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如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。360Please respect copyright.PENANAsAod5r1TIz
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc360Please respect copyright.PENANAMJ74ESaMlT
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。360Please respect copyright.PENANAYGtsBE2IIH
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Link:360Please respect copyright.PENANAD6wJRne0lx
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio360Please respect copyright.PENANAGPiMkxjMoz
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除非Facebook及IG重開侵侵的account,否則我的IG將不會再作更新,只會寄居本土LIHKG及Penana。360Please respect copyright.PENANAdnbUBmtWph
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Ref1:https://www.nature.com/articles/s41586-021-03417-2360Please respect copyright.PENANAkRKeCGVk78