中藥與西藥的比拼經常出現,箇中經常出現的論據就是中藥缺乏科學精密驗證,純粹是依靠經驗及神農嘗百草的方式積聚理論。401Please respect copyright.PENANAPTCudTSTCp
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本篇文章無意將中藥及西藥對衡,而是嘗試以西醫科學角度審視一款中醫藥材,三七。401Please respect copyright.PENANAfy31l5GYSQ
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(圖2)左圖為Panax notoginseng(三七);401Please respect copyright.PENANA8MUDs5xdjv
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中圖為Sedum aizoon(土三七);401Please respect copyright.PENANAN0VQq4WPvl
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而右圖則為Gynura japonica,頻繁被誤當成土三七的藥材。401Please respect copyright.PENANAk5IW16Cv80
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(圖3)不幸的是,這款誤當成土三七的藥材內含名為pyrrolizidine alkaloids (PAs)的化學物;401Please respect copyright.PENANAN9IYIYbOzo
真正的三七及土三七並不含PAs。401Please respect copyright.PENANAlqiLzet8cv
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這些PA化學物進入人體後,會形成DHPA及DHP化學物。401Please respect copyright.PENANAKr2GTKGitV
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而DHPA及DHP化學物會與肝臟內各種蛋白質結合,導致肝臟無法運作正常。401Please respect copyright.PENANAMqBZQF1dI2
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根據資料統計(Ref1),誤當Gynura japonica作為土三七下藥,構成了中國在2017年約10-30%因攝取藥物導致肝臟收損的個案。401Please respect copyright.PENANAutVYU7aOll
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這亦表示,若有經驗不足的中藥醫師或商人胡亂購買藥材的話,將會無意之間害了別人。401Please respect copyright.PENANAmtvK9pSyJg
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能否有系統分配及管理中藥藥材的類別,將會是現今中醫所需面對的問題。401Please respect copyright.PENANAisuhNk3ooX
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有興趣繼續觀看用西醫角度觀看中藥的話,請給予正評及留言,反應熱烈的話將會寫新一集。401Please respect copyright.PENANAEOt3VOjGvy
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如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。401Please respect copyright.PENANAMkp48AWFD4
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc401Please respect copyright.PENANAWDuRi2iPsn
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https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio401Please respect copyright.PENANAuqThL0R6tZ
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有興趣接收科學資訊的話,歡迎follow IG: potatopigtongue。401Please respect copyright.PENANASPURavju4G
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https://www.instagram.com/potatopigtongue/401Please respect copyright.PENANAYQGB5JjPVC
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Ref1:https://www.nature.com/articles/s41401-020-00553-9401Please respect copyright.PENANAAcfG5xoKMy