上集:三十秒科學–Natural Killer Cell486Please respect copyright.PENANA8ORPINY1vw
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上集提及過NK cell有著殺滅癌細胞的本領,如圖中所見,紅色的NK cell遇上綠色的癌細胞後,在1小時打後可以見得到癌細胞開始變形,更在74分鐘打後「灰飛煙滅」。486Please respect copyright.PENANAxDcABMwDm4486Please respect copyright.PENANAC6u7ejJOXi
既然這麼順利,那為何還會有癌症出現呢?486Please respect copyright.PENANA9Nb1JqOJHc
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(圖2)這是因為癌細胞有著各樣的手段對抗NK cell的襲擊,明哲保身。486Please respect copyright.PENANASayuyHO5vN486Please respect copyright.PENANAE5l82OC4D3
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從圖中的例子可以看到,這一次NK cell與癌細胞接觸約36分鐘後,不但沒有襲擊癌細胞,更以那兩名香港警察先鋒對待721的方式逃逸離去,使癌細胞得以安然無恙活下去。486Please respect copyright.PENANAGLI02zWY8y
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(圖3)科學家發現,較能對抗NK cell的癌細胞有著一道應付NK cell的本領,它們遇上NK cell後會快速改變自身的蛋白質結構,將歸納名為actin的蛋白質速速調配至與NK cell的接觸點,形成圖中綠色區域的聚集。486Please respect copyright.PENANA67msLjdCO4486Please respect copyright.PENANAJI2FsVbH12
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這些actin蛋白質的調動,促使抑制NK cell的蛋白質大量且集中聚積到與NK cell的接觸點(上集所指的 – 號組合),導致NK cell失去殺滅癌細胞的功能,並且與癌細胞作出脫離。486Please respect copyright.PENANAoBvgNksiwh
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而沒能對抗NK cell的癌細胞並沒有出現actin蛋白質的調整,相對上因而較易遭受到NK cell的侵襲。486Please respect copyright.PENANAFKzdAIB401
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。486Please respect copyright.PENANAg9rJBlRyr1
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除非Facebook及IG重開侵侵的account,否則我的IG將不會再作更新,只會寄居本土LIHKG及Penana。486Please respect copyright.PENANAMugWeJvh0N
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Ref1:https://cancerres.aacrjournals.org/content/78/19/5631486Please respect copyright.PENANA7DdKniX9JL