免疫細胞中，有一類別名為Natural Killer Cell(NK cell)。492Please respect copyright.ＰＥＮＡＮＡPFtpxiayA3
492Please respect copyright.ＰＥＮＡＮＡ02ipQ5rdbh
它們並不需要抗體的輔助，能夠直接與受病毒感染的細胞或癌細胞接觸，並且能夠在對方的表面開拓出微孔，繼而再將特定的蛋白酶注入對方內部，導致對方啟動自行滅亡的機制。492Please respect copyright.ＰＥＮＡＮＡVwxWUHFuuo
492Please respect copyright.ＰＥＮＡＮＡHDlb7Cadl3
(圖2)NK cell及癌細胞表面均有著形形式式的蛋白質，雙方表面某部分的蛋白質會互相結合，某些組合會促進NK cell啟動殺滅對方的機制(如圖中+號)，而某些組合(圖中-號)則會抑制會NK cell的啟動。492Please respect copyright.ＰＥＮＡＮＡDkvo6gUjlY
492Please respect copyright.ＰＥＮＡＮＡfXzQISBjiM
492Please respect copyright.ＰＥＮＡＮＡ233fTow2BW
這些加加減減組合的互動，最終將會主宰NK cell會否殺滅對方。492Please respect copyright.ＰＥＮＡＮＡ1cpdrVbz6A
492Please respect copyright.ＰＥＮＡＮＡliZAkwZC3m
(圖3)除了加加減減組合的互動，那些表面蛋白質所在的位置亦會影響NK cell殺滅對方的效率。492Please respect copyright.ＰＥＮＡＮＡWVQ3kJAJWW
492Please respect copyright.ＰＥＮＡＮＡbLGYpG9xRy
有研究人員將具有促進NK cell啟動殺滅對方的機制的蛋白質附在玻璃上，分別製作圖餅形狀(圖上)及冬甩形狀(圖下)，雖兩者表面上的蛋白質數量均一模一樣，但NK cell停留在圖餅形的時間卻比冬甩形狀的時間相對上較長。492Please respect copyright.ＰＥＮＡＮＡrkQwUePohP
492Please respect copyright.ＰＥＮＡＮＡNEnbPOGkrf
之所以有這樣的差別，相信是NK cell較多時候無法完整地包圍著冬甩形狀，因此脫離對方的機率亦隨之較高。492Please respect copyright.ＰＥＮＡＮＡGICoZgvklT
492Please respect copyright.ＰＥＮＡＮＡHMshs2T5Ge
換句話說，就算對方表面的蛋白質含量一樣，若然所在位置並不是均整地呈現在每一個角落，亦將有機會影響NK cell殺滅的效率。492Please respect copyright.ＰＥＮＡＮＡrQI8LvLbwM
492Please respect copyright.ＰＥＮＡＮＡzBASpMUpWW
492Please respect copyright.ＰＥＮＡＮＡx6X3M73GS4
492Please respect copyright.ＰＥＮＡＮＡYPlhCGNFpE
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。492Please respect copyright.ＰＥＮＡＮＡjijSCfhfBJ
492Please respect copyright.ＰＥＮＡＮＡ0pdjuVgBBW
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc492Please respect copyright.ＰＥＮＡＮＡKBQwaQFhUM
492Please respect copyright.ＰＥＮＡＮＡ8pKyOwve4y
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。492Please respect copyright.ＰＥＮＡＮＡ5L6DUTVhVw
492Please respect copyright.ＰＥＮＡＮＡoiXe0ZAFn3
Link:492Please respect copyright.ＰＥＮＡＮＡxYjC89KTOs
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio492Please respect copyright.ＰＥＮＡＮＡeon6cvWcwY
492Please respect copyright.ＰＥＮＡＮＡYW85e365aX
492Please respect copyright.ＰＥＮＡＮＡ10MrAlIljs
除非Facebook及IG重開侵侵的account，否則我的IG將不會再作更新，只會寄居本土LIHKG及Penana。492Please respect copyright.ＰＥＮＡＮＡnZQaV4mjub
492Please respect copyright.ＰＥＮＡＮＡCbpfvof49W
Ref1:https://www.frontiersin.org/articles/10.3389/fimmu.2015.00202/full492Please respect copyright.ＰＥＮＡＮＡld4fsK3zyX
Ref2:https://stke.sciencemag.org/content/14/684/eabe2740
492Please respect copyright.ＰＥＮＡＮＡlvikUk31S9
