腸道是人體吸收葡萄糖的主要地方,亦是消化乳糖酵素(Lactase)的聚居地。884Please respect copyright.PENANAZS0Z83XGax
缺乏Lactase的人並不建議進食含有乳糖的產品,否則會釀起肚痾、腹痛、作嘔等症狀,學名為Lactose Intolerance。884Please respect copyright.PENANAWhC6w5X09O
884Please respect copyright.PENANABvKb27wBkQ
884Please respect copyright.PENANASjpuleFt5T
884Please respect copyright.PENANAXTZGYi62f1
同時,腸道亦是寄生蟲的蝸居,飲用不乾淨水的話有機會讓血吸蟲寄生在腸道之中,引起血吸蟲病(Schistosomiasis),為全球第二大僅次於瘧疾(Malaria)的寄生蟲病。884Please respect copyright.PENANAiSPcoLRrrS
884Please respect copyright.PENANAFh9m4Spgli
884Please respect copyright.PENANAG9BdJ8xTJV
(圖2)近日,有科學家發表文章(Ref1),他們研發出一款口服藥物,主要利用豬隻作為動物模型,證實豬隻吞下藥物後的12分鐘會腸道形成厚膜。884Please respect copyright.PENANAoF2bQiceZE
884Please respect copyright.PENANAiHMfJyXf0i
884Please respect copyright.PENANAkqYpgnQdTm
此厚膜不會在其他器官上形成,而在24小時後厚膜亦會自然脫落,排出體外。884Please respect copyright.PENANA0ansob78Uv
884Please respect copyright.PENANAXScGNOvfKF
(圖3)根據口服藥物的配方不同,厚膜的特性亦能隨之轉變。884Please respect copyright.PENANA0ocPQN72iG
884Please respect copyright.PENANAPv90KRJFfL
884Please respect copyright.PENANAHH8sZ05C9U
厚膜可配載消化乳糖酵素(Lactase),對比沒有厚膜,能增強20倍酵素的能力,可消除Lactose Intolerance的問題。884Please respect copyright.PENANANlcnlpGcr0
884Please respect copyright.PENANAnYh4A3DXHh
而增強厚膜密度的話,亦可減少腸道吸收葡萄糖七成能力,這特點尤其受益於糖尿病人,能大幅度阻上血糖飄升。884Please respect copyright.PENANALfnHmcAIOb
884Please respect copyright.PENANABfoAEhDQkn
另外,厚膜亦可配載殺寄生蟲藥(Praziquantel),增加藥物滯留在腸道的時間,更有效率殺滅寄生蟲。884Please respect copyright.PENANAYWQJeEUN3N
884Please respect copyright.PENANAytVLqaCHV5
884Please respect copyright.PENANAtKzvr7SaBM
(圖4)最為振奮的是,此方法在人類腸道組織亦見效,而且藥物對各種實驗室人體細胞亦無呈現有害效果。884Please respect copyright.PENANAKxbbXxZYz5
884Please respect copyright.PENANAONDVFE5gDP
884Please respect copyright.PENANAMzNhl7n458
老鼠服用藥物28日後,體重血壓等一切正常。884Please respect copyright.PENANAT4bolUDFhI
884Please respect copyright.PENANAivMoui9f3A
若然此藥物能進一步在人類進行試驗的話,確立藥物運作正常及不會帶來任何副作用或安全問題的話,絕對大有潛質會成為治理糖尿病的新一代藥物。884Please respect copyright.PENANAUkKT09HMDI
884Please respect copyright.PENANAyAyroKA94N
如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。884Please respect copyright.PENANAZKEZVvOW6y
884Please respect copyright.PENANAUQJ4s5iW72
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc884Please respect copyright.PENANAdp87LYtajX
884Please respect copyright.PENANAbD6EtkWFIq
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。884Please respect copyright.PENANAZmtnGBg8rr
884Please respect copyright.PENANAgmSyWgtK4H
Link:884Please respect copyright.PENANATX8HljGygj
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio884Please respect copyright.PENANAPDwLWESzd6
884Please respect copyright.PENANAacST8a3b3z
884Please respect copyright.PENANAs9hKh7v2PE
有興趣接收科學資訊的話,歡迎follow IG: potatopigtongue。884Please respect copyright.PENANACGeycFwCis
884Please respect copyright.PENANAQQP3LVaBnZ
884Please respect copyright.PENANAIcLpKRR6Zs
884Please respect copyright.PENANA41tdv0xbTU
Ref1:https://stm.sciencemag.org/content/12/558/eabc0441
00
ns 15.158.61.46da2