中藥與西藥的比拼經常出現,箇中經常出現的論據就是中藥缺乏科學精密驗證,純粹是依靠經驗及神農嘗百草的方式積聚理論。381Please respect copyright.PENANAJG8V7BwRaB
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本篇文章無意將中藥及西藥對衡,而是嘗試以西醫科學角度審視一款中醫藥材,三七。381Please respect copyright.PENANAyw8TTE5nFt
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(圖2)左圖為Panax notoginseng(三七);381Please respect copyright.PENANAsW7Lwsnibo
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中圖為Sedum aizoon(土三七);381Please respect copyright.PENANA8im5m5EjPR
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而右圖則為Gynura japonica,頻繁被誤當成土三七的藥材。381Please respect copyright.PENANADNSQfHLkNV
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(圖3)不幸的是,這款誤當成土三七的藥材內含名為pyrrolizidine alkaloids (PAs)的化學物;381Please respect copyright.PENANAyBDyPFZYxV
真正的三七及土三七並不含PAs。381Please respect copyright.PENANAtCjxfSLCPg
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這些PA化學物進入人體後,會形成DHPA及DHP化學物。381Please respect copyright.PENANA24prPTpL5G
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而DHPA及DHP化學物會與肝臟內各種蛋白質結合,導致肝臟無法運作正常。381Please respect copyright.PENANACcFa5TGZUO
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根據資料統計(Ref1),誤當Gynura japonica作為土三七下藥,構成了中國在2017年約10-30%因攝取藥物導致肝臟收損的個案。381Please respect copyright.PENANAoutBXQBhm7
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這亦表示,若有經驗不足的中藥醫師或商人胡亂購買藥材的話,將會無意之間害了別人。381Please respect copyright.PENANACqvhMYeIeW
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能否有系統分配及管理中藥藥材的類別,將會是現今中醫所需面對的問題。381Please respect copyright.PENANAK9rFYQjdIc
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有興趣繼續觀看用西醫角度觀看中藥的話,請給予正評及留言,反應熱烈的話將會寫新一集。381Please respect copyright.PENANASUwbyyo4Ti
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https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio381Please respect copyright.PENANAg9Pu1oz9C2
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有興趣接收科學資訊的話,歡迎follow IG: potatopigtongue。381Please respect copyright.PENANAPgdCvC8Kuc
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https://www.instagram.com/potatopigtongue/381Please respect copyright.PENANAxJ84HYlCbe
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Ref1:https://www.nature.com/articles/s41401-020-00553-9381Please respect copyright.PENANAZgu5PjqeWz