注射武肺疫苗的主要目的,就是誘導身體產生對抗武肺病毒的抗體。430Please respect copyright.PENANAZ7blH2GY2D
430Please respect copyright.PENANAooApQYiypG
430Please respect copyright.PENANAb91OqrvK67
但身體製造抗體需時,而且免疫系統薄弱的人士亦有可能沒法製造足夠數量的抗體。在這層面上,直接注射人造抗體的話,便能免去這兩道隱憂。430Please respect copyright.PENANAy4mMTCDHnA
430Please respect copyright.PENANAwAvFuyJCiP
(圖2)從圖中所見,檢測者身體含有武肺抗體的話,身體的病毒數量相對上亦會較少,反之亦然。430Please respect copyright.PENANACEatD1Kz8d
430Please respect copyright.PENANApaYnXxQEaF
430Please respect copyright.PENANA1EsfnYfrNP
可見病毒數量與體內抗體含量有著反比的關係。430Please respect copyright.PENANAG9iVt6VXSQ
430Please respect copyright.PENANAJuCDmtp5Ec
(圖3)現今有一推斷,體內武肺病毒數量越多的話,出現重症的機會亦會相繼增加。430Please respect copyright.PENANAHA6EFX5w9D
430Please respect copyright.PENANA3tYnQl8pHa
430Please respect copyright.PENANAhzos8hEapS
針對這一點,REGN公司進行臨床測試,為武肺患者注射兩款武肺人造抗體430Please respect copyright.PENANAbEzyL1HPhN
casirivimab (REGN10933) 和imdevimab (REGN10987),430Please respect copyright.PENANAnsIeJmbChj
觀察能否透過注射人造抗體來減低體內病毒的數量(Ref1)。430Please respect copyright.PENANAyZUfic8k15
430Please respect copyright.PENANAajFuZjgMwp
(圖4)分別往測試者注射安慰劑(灰線)、2g人造抗體(藍線)和8g人造抗體(綠線)後,可以見得到接受人造抗體注射的人士,其病毒在體內的下降速度比注射安慰劑的來得更快。430Please respect copyright.PENANAONRyz6a2FN
430Please respect copyright.PENANAMQagasxqAe
430Please respect copyright.PENANAR3UIl51yTE
(圖5)但若然在注射前已被驗出擁有武肺抗體的話,額外的人造抗體注射並不會導致病毒有顯著的加快下跌(右圖);這有可能是體內的抗體本身已足夠應付現況。430Please respect copyright.PENANAkrkTLfewGX
430Please respect copyright.PENANAzabPrBW2QB
430Please respect copyright.PENANAl3JEBEk2X4
430Please respect copyright.PENANAeDgqMVGQpV
(圖6)值得留意的是,本身病毒數量越多的話,人造抗體所促使的病毒量下跌效果便會越見明顯。430Please respect copyright.PENANARjkdij1jbS
430Please respect copyright.PENANAyhuf1JLIrf
430Please respect copyright.PENANAvR2QxaBYxx
亦即是代表當體外病毒數量超過某一定數量的時候,體內自身的抗體便會未能足以應付現況,而此時候所注射的人造抗體便會派上用場。430Please respect copyright.PENANA8wMtC79y6k
430Please respect copyright.PENANAP3N84gS8Ru
(圖7)人造抗體注射後的第28日,其濃度亦相對非常穩定,能給予注射人士一道保護時間。430Please respect copyright.PENANAqTkJqEgiVW
430Please respect copyright.PENANAzLPKZLStWa
430Please respect copyright.PENANABj6afmkvvj
430Please respect copyright.PENANAQol9jX7UI2
人造抗體雖能加快病毒下降的速度,但能否預防重症這一方面並未有充份證據支持。430Please respect copyright.PENANApne1L854fq
430Please respect copyright.PENANA0ydxOBj3MF
而當患者已出現嚴重症狀後,注射人造抗體能否緩和或解決症狀亦是相當成疑。430Please respect copyright.PENANAVhvs1dzkPf
430Please respect copyright.PENANAXnu9ew59bb
但無論如何,若然想達到在短時間內減低體內病毒的數量,人造抗體相信是其中一道的選擇。430Please respect copyright.PENANAyP5NxVtorx
430Please respect copyright.PENANAvFI7EBC3NP
430Please respect copyright.PENANArvSq9lIOqZ
如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。430Please respect copyright.PENANAP6L0RkiARv
430Please respect copyright.PENANAXJrB6wsi8K
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc430Please respect copyright.PENANAKfsPmDTtyt
430Please respect copyright.PENANAw94X2lCDpn
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。430Please respect copyright.PENANA1ryMSgAUnp
430Please respect copyright.PENANAZK6ha0nkDj
Link:430Please respect copyright.PENANAR5eCBVkhYp
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio430Please respect copyright.PENANAsNatvsYTKL
430Please respect copyright.PENANAyCD2IPKnZ0
有興趣接收科學資訊的話,歡迎follow IG: potatopigtongue。430Please respect copyright.PENANAe3Uceg1g7G
430Please respect copyright.PENANASA2txkEc1w
https://www.instagram.com/potatopigtongue/430Please respect copyright.PENANAY16KG2u0OS
430Please respect copyright.PENANAGgVLqpTCur
430Please respect copyright.PENANAh1bk8uOkhP
Ref1:https://www.nejm.org/doi/full/10.1056/NEJMoa2035002430Please respect copyright.PENANAwWV5ogOjpY