癌細胞有各種手段逃避我們身體免疫系統的追捕,其中之一的手段就是在表面上表達名為PDL1的蛋白質。638Please respect copyright.PENANAoNy6vEw3NH
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免疫系統細胞表面的PD1蛋白質與PDL1確認的話,便不會追殺癌細胞,任由惡勢力增長。638Please respect copyright.PENANAyepL1f0O25
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(圖2)用抗體阻擋PD1,導致免疫系統細胞不再受癌細胞蒙騙,繼而懂得消滅癌細胞,就是免疫治療的精髓所在。638Please respect copyright.PENANAIG0bksVr0h
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只不過,若癌細胞沒有表達PDL1蛋白質的話,此方法便不奏效。638Please respect copyright.PENANARMivVZFeb4
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而且就算癌細胞真的是有表達PDL1蛋白質,此方法對某一些病人亦不太見效。638Please respect copyright.PENANAudxtHAKMen
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免疫治療延伸閱讀:https://www.penana.com/article/471125638Please respect copyright.PENANA4RfZhCQr3w
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(圖3)有研究發現,腸道的細菌群組能夠影響免疫治療的效果。638Please respect copyright.PENANA8XzeJ0fzaV
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因此,有臨床研究嘗試將對免疫治療有效的病人的腸道細菌,以手術及口服糞便藥丸的方法移植到對免疫治療無效的病人腸道,試驗能否增強免疫治療的效用。638Please respect copyright.PENANAB0siGDqIRj
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(圖4)利用糞便移植手段,原先對免疫治療無效的病人亦出現顯著的效果。638Please respect copyright.PENANAJq4IuqggSf
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是次研究共有五名試驗者,有三名出現了正面效果。其中一名病患在半個月後,身上的皮膚癌更是完全消失。638Please respect copyright.PENANAZNQtR2p6kJ
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如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。638Please respect copyright.PENANAuawYe3UsfJ
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc638Please respect copyright.PENANAeLthVwHOxB
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。638Please respect copyright.PENANARef4XxAihY
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Link:638Please respect copyright.PENANAmReUvDh8dj
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio638Please respect copyright.PENANAurSRFkxPJF
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基於WhatsApp/Facebook等問題,IG將不會再作更新,只會寄居本土LIHKG及Penana。638Please respect copyright.PENANAzxJYafhcZK
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Ref1:https://science.sciencemag.org/content/early/2020/12/09/science.abb5920638Please respect copyright.PENANAJMSwTJ0XiO