當沙門氏菌處於缺乏營養的環境,例如缺乏鎂(Magnesium)的時候,他們便會停止生長。342Please respect copyright.PENANAKrNoeqcSxc
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而一但營養供應再次充足的時候,他們有能力在短時間內立刻極速生長。342Please respect copyright.PENANA1a8qCmVV7F
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(圖2)當微生物從外部攝取營養後,便能夠將營養轉化成為能量,以ATP物質的方式儲存。342Please respect copyright.PENANAURUsce0xED
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製造蛋白質固然需要使用ATP能量,但摧毀蛋白質的過程中亦需要用上ATP能量才能完成。342Please respect copyright.PENANAxAVbye1Pe4
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(圖3)當外部沒有營養,沙門氏菌自然沒能製成充夠的ATP,那麼需要ATP才能完成的蛋白質摧毀程序亦會因而減慢。342Please respect copyright.PENANA8xGdATMtrz
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在這個情形下,當營養再度充足的時候,他們很快便能找回應有的繁殖速度。342Please respect copyright.PENANAsNkm4weuxn
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(圖4)同一個情況,當外部沒有營養,沙門氏菌自然沒能製成充夠的ATP,但若然在此時候落藥(例如停止蛋白質生產工序,騰出更多ATP能源出來),逼使ATP數量增加,那麼需要ATP才能完成的蛋白質摧毀程序亦會因而繼續全速進行。342Please respect copyright.PENANAvwjXUBDacj
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在這個情形下,當營養再度充足的時候,他們需要更長的時間才能找回應有的繁殖速度。342Please respect copyright.PENANA96IOcIRqMz
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科學家作出一系列的研究(Ref1),發現微生物及酵母在營養短缺的時候,會故意將一些重要的蛋白質保存下來,不讓它們遭受摧毀。342Please respect copyright.PENANAVP5be9paiU
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這些重要的蛋白質,能夠讓他們再度獲得營養的時候得以快速生長。342Please respect copyright.PENANAm6g6RTKOHa
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而當我們利用藥物強迫他們在營養短缺的時候繼續保持蛋白質摧毀工序的話,那些重要的蛋白質亦無可避免遭受摧毀。342Please respect copyright.PENANAVQ69BM8tQ0
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在這個情況下,當他們再度獲得營養後,便要先花時間製作那些重要的蛋白質,才能得以快速生長。342Please respect copyright.PENANA5z5HfreALh
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若果能夠把細菌的蛋白質摧毀工序玩弄得暸如指掌,亦將可以成為一道針對性消滅他們的方法。342Please respect copyright.PENANA6kxKQ8ruRk
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如果想我快啲出文的話,請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark,這對我非常之重要。342Please respect copyright.PENANAR5oNB4aExg
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc342Please respect copyright.PENANALyqjYI2aHq
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」,以課金的方式推動我繼續搜羅資料寫文,多謝。342Please respect copyright.PENANAuMJ6KYYyxd
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Link:342Please respect copyright.PENANAJEY9wXX8uu
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio342Please respect copyright.PENANAx9BMAZcmZN
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基於WhatsApp/Facebook等問題,IG將不會再作更新,只會寄居本土LIHKG及Penana。342Please respect copyright.PENANAxRoLH7mBPt
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Ref1:https://stke.sciencemag.org/content/14/667/eabc4235342Please respect copyright.PENANA0QbQaQelKl