因人而異，膀胱/尿袋 (Urinary Bladder)一般來說可以儲存300-500ml尿液。984Please respect copyright.ＰＥＮＡＮＡHN56sYDJJm
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尿液的其中一個功能，就是將體內的毒素或細菌排出，而膀胱經常有大量尿液儲存，為罪惡的蘊藏之所，體內的警署。984Please respect copyright.ＰＥＮＡＮＡCKauv6y23o
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想深一層，身體的細菌經由尿液聚首一堂，膀胱豈不是非常容易令受到感染?984Please respect copyright.ＰＥＮＡＮＡty6YAnFyGv
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（致病的細菌及毒素亦可從糞便排出）984Please respect copyright.ＰＥＮＡＮＡzROLnPO5sr
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（圖2）尿調理素(Uromodulin/Tamm–Horsfall Protein)是尿液其中一種常見的主要蛋白，主要在腎臟管道生產。984Please respect copyright.ＰＥＮＡＮＡKR6EOJYMXH
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它被認定為有抵禦細菌感染的作用，但一直以來也沒有充分的證據得以證明。984Please respect copyright.ＰＥＮＡＮＡEfBmShZJSZ
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近日，有科學家利用最新的電子顯微鏡技術及各種實驗輔證（Ref1)，終於確立得到尿調理素抵禦細菌感染的功能。984Please respect copyright.ＰＥＮＡＮＡhTPDoDCtCe
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（圖3）先簡單重溫一下細菌的外部結構，今次我們會特別著重提及Pili，它賦予細菌與外部接觸的能力。984Please respect copyright.ＰＥＮＡＮＡGiHFAknk6V
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（圖4）左邊是文中的圖片，黃色箭嘴頭所指示的就是細菌的pili，它能夠與uromodulin建立非常穩定的連結；984Please respect copyright.ＰＥＮＡＮＡXOGn8zxEyu
箇中的連結需要糖份組織的幫助。984Please respect copyright.ＰＥＮＡＮＡmpYjE7FyNA
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（圖5）Uromodulin在尿液的大量存在，將會強迫致病的大腸桿菌聚在一起，以免大腸桿菌能夠與膀胱內壁接觸及進行感染。984Please respect copyright.ＰＥＮＡＮＡ5wuXqX4DBZ
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以壓倒性的數量，簡單將致病的大腸桿菌聚集及封鎖在一起，這種防禦機制相對地直接簡單。984Please respect copyright.ＰＥＮＡＮＡxH4D7rCg6N
至於Uromodulin能否與所有已知的致命細菌結合、會否有著其他的機制及功能，還需要進一步的調查。984Please respect copyright.ＰＥＮＡＮＡw12zTyCmNl
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。984Please respect copyright.ＰＥＮＡＮＡknpaYDfngY
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc984Please respect copyright.ＰＥＮＡＮＡflScoqpBai
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。984Please respect copyright.ＰＥＮＡＮＡqqSdojmIyF
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Link:984Please respect copyright.ＰＥＮＡＮＡMcqYDJIXG4
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio984Please respect copyright.ＰＥＮＡＮＡgPymOXWjEV
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有興趣接收科普資訊的話，歡迎follow IG: potatopigtongue。984Please respect copyright.ＰＥＮＡＮＡ2uaSGnJWQ7
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Ref1:https://science.sciencemag.org/content/369/6506/1005?ijkey=e112b23dc73c7c7bd746a5711869e4bf44026346&keytype2=tf_ipsecsha
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