暗瘡對大部份人來說可謂是一道萬惡的存在,尤其是愛靚唔愛命的女士們的公敵。549Please respect copyright.PENANAwXmYrhDDjc
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在講述暗瘡的形成之前,我們首先需要了解一下皮膚的背景資料。549Please respect copyright.PENANAL65PPBwX34
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(圖1)皮膚是人類最大的器官,它是我們一道抵禦外來物入侵的防線,同時亦提供了一個優良環境給予各式各樣的細菌及真菌成長及聚居。549Please respect copyright.PENANAXWWNrZoZpr
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除皮膚表層外,那些細菌及真菌亦可聚居在髮囊、負責散熱的汗腺及負責分泌油脂的皮脂腺裡頭。549Please respect copyright.PENANAUciVYRUlbi
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(圖2)皮膚最外層的細胞全都是已死的細胞(Dead Cells),學名為Enucleated keratinocytes。549Please respect copyright.PENANAVzvXLF1B6x
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這些已死的細胞會不斷脫落,大概每日總共會脫落50億這些已死的細胞,而下層已死的細胞會逐漸補上,日復如是。549Please respect copyright.PENANAfmKD8ZfjmS
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(圖3)暗瘡的形成,與那些表層細胞有著莫大的關係。549Please respect copyright.PENANAW8KmL85Rvw
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以下為形式暗瘡的簡略三步曲:549Please respect copyright.PENANAizBJALcIjn
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1.皮膚表面已死細胞脫落到髮囊裡頭。549Please respect copyright.PENANAcTuNIPBRSI
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2.皮脂腺釋出油脂,因已死細胞阻窒通道,導致油脂無法離開,久而久之便成為黑頭。549Please respect copyright.PENANAmXxAAKZN6f
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3.聚居在油脂腺的細菌分解油脂為更簡單結構的油脂物,而這些油脂物觸動發炎反應,造就暗瘡的誕生。549Please respect copyright.PENANAVE4tPqpRGC
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(圖4)青春期荷爾蒙作怪,油脂分泌特別旺盛,所以年青人特別容易生暗瘡。549Please respect copyright.PENANA3mkS1yIQGj
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但是,有些人就算做足日常護理都會特別容易生暗瘡,而有些不愛日常臉部護理的懶鬼就死都唔會生暗瘡,裡頭究竟是甚麼原因呢?549Please respect copyright.PENANAvGvTwCmtcC
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(圖5)大量的研究指出,Cutibacterium acnes (C. acnes)是人體皮膚最常見且數量眾多的一種細菌,亦是暗瘡促成的元兇。549Please respect copyright.PENANALsQplJBkLY
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易生暗瘡以及不易生暗瘡的人,C. acnes 數量並沒有太大的分別,但品種上有著一道顯著的分別。549Please respect copyright.PENANAGQygIChLg8
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易生暗瘡人皮膚上的C. acnes 品種更有效率代謝皮脂腺所釋出的油脂,亦即是更容易促成發炎反應形成暗瘡。549Please respect copyright.PENANAvHnohNbYgO
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(圖6)現時治理暗瘡的手法大多會用上benzoyl peroxide或retinoic acid,目的是刺激皮膚及減低油脂的分泌。549Please respect copyright.PENANAYlwRP53JkG
隨著科技的進步及對皮膚細菌的認識,科學界有著思想上的轉變,認為改變皮膚上的細菌群組才是對付暗瘡治標且治本的方法。549Please respect copyright.PENANA4Wwg93TiBJ
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現時只至有三種治理暗瘡的嶄新手段正進行臨床階段之中。549Please respect copyright.PENANAQMjjom1U7g
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1.把不易生暗瘡的人皮膚表面上的C. acnes放到易生暗瘡人士上,企圖以良幣消除劣幣的方式取代舊有的C. acnes。549Please respect copyright.PENANA7zXb0dSuhh
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2.把失去化謝油脂能力的C. acnes取代舊有的C. acnes。549Please respect copyright.PENANA3sPzP93mRj
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3.把懂得釋放抑制發炎化應化學物的C. acnes取代舊有的C. acnes。549Please respect copyright.PENANAVQoB1OY2r7
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今年的十月相信會有這些臨床研究的進一步結果的分析,但願這種治療方式會為暗瘡人士帶來一股新希望。549Please respect copyright.PENANA0ap1Ia3fJ2
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